Wilms’ Tumor Project

Dr Peter Moon & Oscar Gerard

Wilms’ Tumor Website

Project Centers: Malawi, Ghana, Cameroon, Tanzania, Uganda, Ethiopia

Twinning Partner: VU University Medical Center, Amsterdam, The Netherlands

Other Partners: SIOP (International Society for Pediatric Oncology)

Project Leads: 

  • Prof. Elizabeth Molyeux & Dr. George Chagaluka – Malawi
  • Dr. Lorna Awo Renner & Dr Vivian Paintsil – Ghana
  • Dr. Francine Kouya – Cameroon
  • Dr. Trisha Scanlan – Tanzania
  • Dr. Joyce Kambugu & Dr Jackson Orem – Uganda
  • Dr. Yassar Celiker – Ethiopia

Project Mentors: Dr. Trijn Israels

Start Date: January 2014

Project Background: It is known that survival from childhood cancer in sub-Saharan Africa is possible. Twinning initiatives in the region have produced considerable progress over the last few years. Wilms’ tumour is a relatively common and treatable kidney tumour with survival rates of around 85% in high-income countries. Treatment is multi-disciplinary and involves paediatricians, surgeons, nurses, radiologists and pathologists.

A multi-disciplinary group of African clinicians and international experts has produced a SIOP PODC consensus treatment guideline adapted to local circumstances. Emphasis is placed on:

  •  Social support to enable patients to complete treatment
  •  The provision of adequate supportive care
  •  The role of ultrasonography in diagnosis
  •  Pre-operative chemotherapy with a reduced dosage for malnourished children
  •  Post-operative chemotherapy based on surgical staging